Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination

Meiotic recombination is initiated by programmed DNA double-strand break (DSB) formation mediated by Spo11. DSBs occur with frequency in chromosomal regions called hot domains but are seldom seen in cold domains. To obtain insights into the determinants of the distribution of meiotic DSBs, we examin...

Descripción completa

Detalles Bibliográficos
Autores principales: Fukuda, Tomoyuki, Kugou, Kazuto, Sasanuma, Hiroyuki, Shibata, Takehiko, Ohta, Kunihiro
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241902/
https://www.ncbi.nlm.nih.gov/pubmed/18096626
http://dx.doi.org/10.1093/nar/gkm1082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241902/
https://www.ncbi.nlm.nih.gov/pubmed/18096626
http://dx.doi.org/10.1093/nar/gkm1082

Ejemplares similares