Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling

We examined the role of post-transcriptional mechanisms in controlling utrophin A mRNA expression in slow versus fast skeletal muscles. First, we determined that the half-life of utrophin A mRNA is significantly shorter in the presence of proteins isolated from fast muscles. Direct plasmid injection...

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Detalles Bibliográficos
Autores principales: Chakkalakal, Joe V., Miura, Pedro, Bélanger, Guy, Michel, Robin N., Jasmin, Bernard J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241908/
https://www.ncbi.nlm.nih.gov/pubmed/18084024
http://dx.doi.org/10.1093/nar/gkm1107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241908/
https://www.ncbi.nlm.nih.gov/pubmed/18084024
http://dx.doi.org/10.1093/nar/gkm1107

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