Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited?

Although neither kinase-dead human epidermal growth factor receptor (HER)3 nor orphan HER2 can be activated by HER-related ligands on their own, the formation of HER2/HER3 heterodimers creates the most mitogenic and transforming receptor complex within the HER (erbB) family of transmembrane receptor...

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Detalles Bibliográficos
Autores principales: Menendez, Javier A, Lupu, Ruth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242662/
https://www.ncbi.nlm.nih.gov/pubmed/17983482
http://dx.doi.org/10.1186/bcr1773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242662/
https://www.ncbi.nlm.nih.gov/pubmed/17983482
http://dx.doi.org/10.1186/bcr1773

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