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The effect of deletion of the orphan G – protein coupled receptor (GPCR) gene MrgE on pain-like behaviours in mice

BACKGROUND: The orphan GPCR MrgE is one of an extended family of GPCRs that are expressed in dorsal root ganglia (DRG). Based on these expression patterns it has been suggested that GPCRs like MrgE may play a role in nociception however, to date, no direct supporting evidence has emerged. We generat...

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Detalles Bibliográficos
Autores principales: Cox, Peter J, Pitcher, Tom, Trim, Steven A, Bell, Christine H, Qin, Wenning, Kinloch, Ross A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242784/
https://www.ncbi.nlm.nih.gov/pubmed/18197975
http://dx.doi.org/10.1186/1744-8069-4-2