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Unintentional miRNA Ablation Is a Risk Factor in Gene Knockout Studies: A Short Report

One of the most powerful techniques for studying the function of a gene is to disrupt the expression of that gene using genetic engineering strategies such as targeted recombination or viral integration of gene trap cassettes. The tremendous utility of these tools was recognized this year with the a...

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Detalles Bibliográficos
Autores principales: Osokine, Ivan, Hsu, Ruby, Loeb, Gabriel B, McManus, Michael T
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242815/
https://www.ncbi.nlm.nih.gov/pubmed/18282110
http://dx.doi.org/10.1371/journal.pgen.0040034