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Expression Profiles Reveal Parallel Evolution of Epistatic Interactions Involving the CRP Regulon in Escherichia coli

The extent and nature of epistatic interactions between mutations are issues of fundamental importance in evolutionary biology. However, they are difficult to study and their influence on adaptation remains poorly understood. Here, we use a systems-level approach to examine epistatic interactions th...

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Detalles Bibliográficos
Autores principales: Cooper, Tim F, Remold, Susanna K, Lenski, Richard E, Schneider, Dominique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242816/
https://www.ncbi.nlm.nih.gov/pubmed/18282111
http://dx.doi.org/10.1371/journal.pgen.0040035