Modeling an Evolutionary Conserved Circadian Cis-Element

Circadian oscillator networks rely on a transcriptional activator called CLOCK/CYCLE (CLK/CYC) in insects and CLOCK/BMAL1 or NPAS2/BMAL1 in mammals. Identifying the targets of this heterodimeric basic-helix-loop-helix (bHLH) transcription factor poses challenges and it has been difficult to decipher...

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Detalles Bibliográficos
Autores principales: Paquet, Eric R, Rey, Guillaume, Naef, Felix
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242825/
https://www.ncbi.nlm.nih.gov/pubmed/18282089
http://dx.doi.org/10.1371/journal.pcbi.0040038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242825/
https://www.ncbi.nlm.nih.gov/pubmed/18282089
http://dx.doi.org/10.1371/journal.pcbi.0040038

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