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Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA

Pregnancy-associated malaria is caused by Plasmodium falciparum malaria parasites binding specifically to chondroitin sulfate A in the placenta. This sequestration of parasites is a major cause of low birth weight in infants and anemia in the mothers. VAR2CSA, a polymorphic multi-domain protein of t...

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Detalles Bibliográficos
Autores principales: Andersen, Pernille, Nielsen, Morten A, Resende, Mafalda, Rask, Thomas S, Dahlbäck, Madeleine, Theander, Thor, Lund, Ole, Salanti, Ali
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242842/
https://www.ncbi.nlm.nih.gov/pubmed/18282103
http://dx.doi.org/10.1371/journal.ppat.0040042