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Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA
Pregnancy-associated malaria is caused by Plasmodium falciparum malaria parasites binding specifically to chondroitin sulfate A in the placenta. This sequestration of parasites is a major cause of low birth weight in infants and anemia in the mothers. VAR2CSA, a polymorphic multi-domain protein of t...
Autores principales: | Andersen, Pernille, Nielsen, Morten A, Resende, Mafalda, Rask, Thomas S, Dahlbäck, Madeleine, Theander, Thor, Lund, Ole, Salanti, Ali |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242842/ https://www.ncbi.nlm.nih.gov/pubmed/18282103 http://dx.doi.org/10.1371/journal.ppat.0040042 |
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