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A Cross-Talk between TrkB and Ret Tyrosine Kinases Receptors Mediates Neuroblastoma Cells Differentiation

Understanding the interplay between intracellular signals initiated by multiple receptor tyrosine kinases (RTKs) to give the final cell phenotype is a major pharmacological challenge. Retinoic acid (RA)-treatment of neuroblastoma (NB) cells implicates activation of Ret and TrkB RTKs as critical step...

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Detalles Bibliográficos
Autores principales: Esposito, Carla Lucia, D'Alessio, Amelia, de Franciscis, Vittorio, Cerchia, Laura
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242850/
https://www.ncbi.nlm.nih.gov/pubmed/18286198
http://dx.doi.org/10.1371/journal.pone.0001643