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Expression, purification and preliminary crystallographic analysis of oligopeptidase B from Trypanosoma brucei

African sleeping sickness, also called trypanosomiasis, is a significant cause of morbidity and mortality in sub-Saharan Africa. Peptidases from Trypanosoma brucei, the causative agent, include the serine peptidase oligopeptidase B, a documented virulence factor and therapeutic target. Determination...

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Detalles Bibliográficos
Autores principales: Rea, Dean, Hazell, Carole, Andrews, Norma W., Morty, Rory E., Fülöp, Vilmos
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242912/
https://www.ncbi.nlm.nih.gov/pubmed/16880564
http://dx.doi.org/10.1107/S1744309106027874