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Hepatic oxidative DNA damage is associated with increased risk for hepatocellular carcinoma in chronic hepatitis C

Although the oxidative stress frequently occurs in patients with chronic hepatitis C, its role in future hepatocellular carcinoma (HCC) development is unknown. Hepatic 8-hydroxydeoxyguanosine (8-OHdG) was quantified using liver biopsy samples from 118 naïve patients who underwent liver biopsy from 1...

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Detalles Bibliográficos
Autores principales: Tanaka, H, Fujita, N, Sugimoto, R, Urawa, N, Horiike, S, Kobayashi, Y, Iwasa, M, Ma, N, Kawanishi, S, Watanabe, S, Kaito, M, Takei, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243145/
https://www.ncbi.nlm.nih.gov/pubmed/18231107
http://dx.doi.org/10.1038/sj.bjc.6604204