G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

Rigorous quality control steps, termed checkpoints, tightly regulate progression through the cell cycle. DNA-damaging chemotherapy and radiation activate functional cellular checkpoints. These checkpoints can facilitate DNA repair and promote cell death in unrepaired cells. There are at least three...

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Detalles Bibliográficos
Autores principales: Bucher, N, Britten, C D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243162/
https://www.ncbi.nlm.nih.gov/pubmed/18231106
http://dx.doi.org/10.1038/sj.bjc.6604208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243162/
https://www.ncbi.nlm.nih.gov/pubmed/18231106
http://dx.doi.org/10.1038/sj.bjc.6604208

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