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Peptide ligand screening of α-synuclein aggregation modulators by in silico panning
BACKGROUND: α-Synuclein is a Parkinson's-disease-related protein. It forms aggregates in vivo, and these aggregates cause cell cytotoxicity. Aggregation inhibitors are expected to reduce α-synuclein cytotoxicity, and an aggregation accelerator has recently been reported to reduce α-synuclein cy...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244645/ https://www.ncbi.nlm.nih.gov/pubmed/18005454 http://dx.doi.org/10.1186/1471-2105-8-451 |