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Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques

RATIONALE: Selective phosphodiesterase (PDE) inhibitors improve the formation of hippocampus-dependent memories in several rodent models of cognition. However, studies evaluating the effects of PDE inhibition on prefrontal cortex-dependent cognition and in monkeys are rare. OBJECTIVES: The present s...

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Detalles Bibliográficos
Autores principales: Rutten, K., Basile, J. L., Prickaerts, J., Blokland, A., Vivian, J. A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244695/
https://www.ncbi.nlm.nih.gov/pubmed/18034336
http://dx.doi.org/10.1007/s00213-007-0999-1