The Gammaherpesvirus m2 Protein Manipulates the Fyn/Vav Pathway through a Multidocking Mechanism of Assembly

To establish latent infections in B-cells, gammaherpesviruses express proteins in the infected B-cells of the host that spuriously activate signalling pathways located downstream of the B-cell receptor. One such protein is M2, a murine gammaherpesvirus 68-encoded molecule that activates the Vav1/Rac...

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Detalles Bibliográficos
Autores principales: Pires de Miranda, Marta, Alenquer, Marta, Marques, Sofia, Rodrigues, Lénia, Lopes, Filipa, Bustelo, Xosé R., Simas, J. Pedro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244710/
https://www.ncbi.nlm.nih.gov/pubmed/18301737
http://dx.doi.org/10.1371/journal.pone.0001654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244710/
https://www.ncbi.nlm.nih.gov/pubmed/18301737
http://dx.doi.org/10.1371/journal.pone.0001654

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