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The Gammaherpesvirus m2 Protein Manipulates the Fyn/Vav Pathway through a Multidocking Mechanism of Assembly
To establish latent infections in B-cells, gammaherpesviruses express proteins in the infected B-cells of the host that spuriously activate signalling pathways located downstream of the B-cell receptor. One such protein is M2, a murine gammaherpesvirus 68-encoded molecule that activates the Vav1/Rac...
Autores principales: | Pires de Miranda, Marta, Alenquer, Marta, Marques, Sofia, Rodrigues, Lénia, Lopes, Filipa, Bustelo, Xosé R., Simas, J. Pedro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244710/ https://www.ncbi.nlm.nih.gov/pubmed/18301737 http://dx.doi.org/10.1371/journal.pone.0001654 |
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