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Extending pathways based on gene lists using InterPro domain signatures

BACKGROUND: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly used and well established technique to test for the statistically significant over-representation of particular pathways...

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Detalles Bibliográficos
Autores principales: Hahne, Florian, Mehrle, Alexander, Arlt, Dorit, Poustka, Annemarie, Wiemann, Stefan, Beissbarth, Tim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245903/
https://www.ncbi.nlm.nih.gov/pubmed/18177498
http://dx.doi.org/10.1186/1471-2105-9-3