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Preventing DNA over-replication: a Cdk perspective
The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis. When controls fail, DNA over-replication ensues: individual origins fire more than once per S-phase (re-replication) or consecutive S-phases occur...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245919/ https://www.ncbi.nlm.nih.gov/pubmed/18211690 http://dx.doi.org/10.1186/1747-1028-3-3 |