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Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil

BACKGROUND: Lamivudine is an oral nucleoside analogue widely used for the treatment of chronic hepatitis B. The main limitation of lamivudine use is the selection of resistant mutations that increases with time of utilization. Hepatitis B virus (HBV) isolates have been classified into eight genotype...

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Detalles Bibliográficos
Autores principales: Bottecchia, Marcelle, Souto, Francisco JD, Ó, Kycia MR, Amendola, Marcia, Brandão, Carlos E, Niel, Christian, Gomes, Selma A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245951/
https://www.ncbi.nlm.nih.gov/pubmed/18211717
http://dx.doi.org/10.1186/1471-2180-8-11