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Synthesis, Structural Characterization, and Cytotoxic Activity of Novel Paramagnetic Platinum Hematoporphyrin IX Complexes: Potent Antitumor Agents

Three novel stable Pt(III) complexes with distorted octahedral structure and [Formula: see text] ground state have been obtained in the course of Pt(II)-hematoporphyrin IX ((7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H-23H-porphyn-2,18-dipropionic acid), Hp) interaction in alkaline aqueous med...

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Detalles Bibliográficos
Autores principales: Gencheva, G., Tsekova, D., Gochev, G., Momekov, G., Tyuliev, G., Skumryev, V., Karaivanova, M., Bontchev, P. R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246075/
https://www.ncbi.nlm.nih.gov/pubmed/18309370
http://dx.doi.org/10.1155/2007/67376