Cargando…

Single-cell duplex RT-LATE-PCR reveals Oct4 and Xist RNA gradients in 8-cell embryos

BACKGROUND: The formation of two distinctive cell lineages in preimplantation mouse embryos is characterized by differential gene expression. The cells of the inner cell mass are pluripotent and express high levels of Oct4 mRNA, which is down-regulated in the surrounding trophectoderm. In contrast,...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartshorn, Cristina, Eckert, Judith J, Hartung, Odelya, Wangh, Lawrence J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246118/
https://www.ncbi.nlm.nih.gov/pubmed/18067662
http://dx.doi.org/10.1186/1472-6750-7-87