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Regulation of heme oxygenase-1 mRNA deadenylation and turnover in NIH3T3 cells by nitrosative or alkylation stress

BACKGROUND: Heme oxygenase-1 (HO-1) catalizes heme degradation, and is considered one of the most sensitive indicators of cellular stress. Previous work in human fibroblasts has shown that HO-1 expression is induced by NO, and that transcriptional induction is only partially responsible; instead, th...

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Detalles Bibliográficos
Autores principales: Leautaud, Veronica, Demple, Bruce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246143/
https://www.ncbi.nlm.nih.gov/pubmed/18096048
http://dx.doi.org/10.1186/1471-2199-8-116