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DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines

BACKGROUND: DNA hypermethylation events and other epimutations occur in many neoplasms, producing gene expression changes that contribute to neoplastic transformation, tumorigenesis, and tumor behavior. Some human cancers exhibit a hypermethylator phenotype, characterized by concurrent DNA methylati...

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Detalles Bibliográficos
Autores principales: Roll, J Devon, Rivenbark, Ashley G, Jones, Wendell D, Coleman, William B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246151/
https://www.ncbi.nlm.nih.gov/pubmed/18221536
http://dx.doi.org/10.1186/1476-4598-7-15