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DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
BACKGROUND: DNA hypermethylation events and other epimutations occur in many neoplasms, producing gene expression changes that contribute to neoplastic transformation, tumorigenesis, and tumor behavior. Some human cancers exhibit a hypermethylator phenotype, characterized by concurrent DNA methylati...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246151/ https://www.ncbi.nlm.nih.gov/pubmed/18221536 http://dx.doi.org/10.1186/1476-4598-7-15 |