Cargando…
DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
BACKGROUND: DNA hypermethylation events and other epimutations occur in many neoplasms, producing gene expression changes that contribute to neoplastic transformation, tumorigenesis, and tumor behavior. Some human cancers exhibit a hypermethylator phenotype, characterized by concurrent DNA methylati...
Autores principales: | Roll, J Devon, Rivenbark, Ashley G, Jones, Wendell D, Coleman, William B |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246151/ https://www.ncbi.nlm.nih.gov/pubmed/18221536 http://dx.doi.org/10.1186/1476-4598-7-15 |
Ejemplares similares
-
Loss of post-transcriptional regulation of DNMT3b by microRNAs: A possible molecular mechanism for the hypermethylation defect observed in a subset of breast cancer cell lines
por: SANDHU, RUPNINDER, et al.
Publicado: (2012) -
Dysregulation of microRNA expression drives aberrant DNA hypermethylation in basal-like breast cancer
por: SANDHU, RUPNINDER, et al.
Publicado: (2013) -
DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggressiveness of adrenocortical carcinoma
por: Kerdivel, Gwenneg, et al.
Publicado: (2023) -
Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1
por: Wiseman, Ashley K., et al.
Publicado: (2022) -
GSK3B Overexpression Alleviates Posttraumatic Osteoarthritis in Mice by Promoting DNMT1-Mediated Hypermethylation of NR4A3 Promoter
por: Lv, Zhou, et al.
Publicado: (2022)