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Peripherally-Derived BDNF Promotes Regeneration of Ascending Sensory Neurons after Spinal Cord Injury

BACKGROUND: The blood brain barrier (BBB) and truncated trkB receptor on astrocytes prevent the penetration of brain derived neurotrophic factor (BDNF) applied into the peripheral (PNS) and central nervous system (CNS) thus restrict its application in the treatment of nervous diseases. As BDNF is an...

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Detalles Bibliográficos
Autores principales: Song, Xing-Yun, Li, Fang, Zhang, Feng-He, Zhong, Jin-Hua, Zhou, Xin-Fu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246162/
https://www.ncbi.nlm.nih.gov/pubmed/18320028
http://dx.doi.org/10.1371/journal.pone.0001707