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Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection

INTRODUCTION: The receptor for advanced glycation end products (RAGE), a multi-ligand member of the immunoglobulin superfamily, contributes to acute and chronic disease processes, including sepsis. METHODS: We studied the possible therapeutic role of RAGE inhibition in the cecal ligation and punctur...

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Detalles Bibliográficos
Autores principales: Lutterloh, Emily C, Opal, Steven M, Pittman, Debra D, Keith, James C, Tan, Xiang-Yang, Clancy, Brian M, Palmer, Helen, Milarski, Kim, Sun, Ying, Palardy, John E, Parejo, Nicholas A, Kessimian, Noubar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246216/
https://www.ncbi.nlm.nih.gov/pubmed/18042296
http://dx.doi.org/10.1186/cc6184