Inorganic pyrophosphate generation by transforming growth factor-beta-1 is mainly dependent on ANK induction by Ras/Raf-1/extracellular signal-regulated kinase pathways in chondrocytes

ANK is a multipass transmembrane protein transporter thought to play a role in the export of intracellular inorganic pyrophosphate and so to contribute to the pathophysiology of chondrocalcinosis. As transforming growth factor-beta-1 (TGF-β1) was shown to favor calcium pyrophosphate dihydrate deposi...

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Detalles Bibliográficos
Autores principales: Cailotto, Frederic, Bianchi, Arnaud, Sebillaud, Sylvie, Venkatesan, Narayanan, Moulin, David, Jouzeau, Jean-Yves, Netter, Patrick
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246241/
https://www.ncbi.nlm.nih.gov/pubmed/18034874
http://dx.doi.org/10.1186/ar2330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246241/
https://www.ncbi.nlm.nih.gov/pubmed/18034874
http://dx.doi.org/10.1186/ar2330

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