Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes

We demonstrate that loss-of-function yeast phenotypes are predictable by guilt-by-association in functional gene networks. Testing 1,102 loss-of-function phenotypes from genome-wide assays of yeast reveals predictability of diverse phenotypes, spanning cellular morphology, growth, metabolism, and qu...

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Detalles Bibliográficos
Autores principales: McGary, Kriston L, Lee, Insuk, Marcotte, Edward M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246260/
https://www.ncbi.nlm.nih.gov/pubmed/18053250
http://dx.doi.org/10.1186/gb-2007-8-12-r258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246260/
https://www.ncbi.nlm.nih.gov/pubmed/18053250
http://dx.doi.org/10.1186/gb-2007-8-12-r258

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