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Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes
We demonstrate that loss-of-function yeast phenotypes are predictable by guilt-by-association in functional gene networks. Testing 1,102 loss-of-function phenotypes from genome-wide assays of yeast reveals predictability of diverse phenotypes, spanning cellular morphology, growth, metabolism, and qu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246260/ https://www.ncbi.nlm.nih.gov/pubmed/18053250 http://dx.doi.org/10.1186/gb-2007-8-12-r258 |