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Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

BACKGROUND: In vertebrates, tandem arrays of TTAGGG hexamers are present at both telomeres and intrachromosomal sites (interstitial telomeric sequences (ITSs)). We previously showed that, in primates, ITSs were inserted during the repair of DNA double-strand breaks and proposed that they could arise...

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Detalles Bibliográficos
Autores principales: Nergadze, Solomon G, Santagostino, Marco Andrea, Salzano, Alberto, Mondello, Chiara, Giulotto, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246262/
https://www.ncbi.nlm.nih.gov/pubmed/18067655
http://dx.doi.org/10.1186/gb-2007-8-12-r260