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Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution
BACKGROUND: In vertebrates, tandem arrays of TTAGGG hexamers are present at both telomeres and intrachromosomal sites (interstitial telomeric sequences (ITSs)). We previously showed that, in primates, ITSs were inserted during the repair of DNA double-strand breaks and proposed that they could arise...
Autores principales: | Nergadze, Solomon G, Santagostino, Marco Andrea, Salzano, Alberto, Mondello, Chiara, Giulotto, Elena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246262/ https://www.ncbi.nlm.nih.gov/pubmed/18067655 http://dx.doi.org/10.1186/gb-2007-8-12-r260 |
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