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Determining promoter location based on DNA structure first-principles calculations

A new method for the prediction of promoter regions based on atomic molecular dynamics simulations of small oligonucleotides has been developed. The method works independently of gene structure conservation and orthology and of the presence of detectable sequence features. Results obtained with our...

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Detalles Bibliográficos
Autores principales: Goñi, J Ramon, Pérez, Alberto, Torrents, David, Orozco, Modesto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246265/
https://www.ncbi.nlm.nih.gov/pubmed/18072969
http://dx.doi.org/10.1186/gb-2007-8-12-r263