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Quantification of global transcription patterns in prokaryotes using spotted microarrays

We describe an analysis, applicable to any spotted microarray dataset produced using genomic DNA as a reference, that quantifies prokaryotic levels of mRNA on a genome-wide scale. Applying this to Mycobacterium tuberculosis, we validate the technique, show a correlation between level of expression a...

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Detalles Bibliográficos
Autores principales: Sidders, Ben, Withers, Mike, Kendall, Sharon L, Bacon, Joanna, Waddell, Simon J, Hinds, Jason, Golby, Paul, Movahedzadeh, Farahnaz, Cox, Robert A, Frita, Rosangela, ten Bokum, Annemieke MC, Wernisch, Lorenz, Stoker, Neil G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246267/
https://www.ncbi.nlm.nih.gov/pubmed/18078514
http://dx.doi.org/10.1186/gb-2007-8-12-r265