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CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novo gene prediction

We describe CONTRAST, a gene predictor which directly incorporates information from multiple alignments rather than employing phylogenetic models. This is accomplished through the use of discriminative machine learning techniques, including a novel training algorithm. We use a two-stage approach, in...

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Detalles Bibliográficos
Autores principales: Gross, Samuel S, Do, Chuong B, Sirota, Marina, Batzoglou, Serafim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246271/
https://www.ncbi.nlm.nih.gov/pubmed/18096039
http://dx.doi.org/10.1186/gb-2007-8-12-r269