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Harnessing naturally randomized transcription to infer regulatory relationships among genes

We develop an approach utilizing randomized genotypes to rigorously infer causal regulatory relationships among genes at the transcriptional level, based on experiments in which genotyping and expression profiling are performed. This approach can be used to build transcriptional regulatory networks...

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Detalles Bibliográficos
Autores principales: Chen, Lin S, Emmert-Streib, Frank, Storey, John D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246293/
https://www.ncbi.nlm.nih.gov/pubmed/17931418
http://dx.doi.org/10.1186/gb-2007-8-10-r219