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A BAC clone fingerprinting approach to the detection of human genome rearrangements
We present a method, called fingerprint profiling (FPP), that uses restriction digest fingerprints of bacterial artificial chromosome clones to detect and classify rearrangements in the human genome. The approach uses alignment of experimental fingerprint patterns to in silico digests of the sequenc...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246298/ https://www.ncbi.nlm.nih.gov/pubmed/17953769 http://dx.doi.org/10.1186/gb-2007-8-10-r224 |