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Development of drug resistance in a human epidermoid lung carcinoma xenograft line.

The development of resistance to vincristine, actinomycin D and cisplatin has been examined in a human epidermoid lung carcinoma xenograft line (HXL 55) growing in nude mice. Treatment of HXL 55 with 1 mg kg-1 vincristine or 0.5 mg kg-1 actinomycin D once in each in vivo passage resulted in a rapid...

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Detalles Bibliográficos
Autores principales: Mattern, J., Bak, M., Hoever, K. H., Volm, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246496/
https://www.ncbi.nlm.nih.gov/pubmed/3166890