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Interactions of doxorubicin and cis-platin in squamous carcinoma cells in culture.

Doxorubicin (DXR) has a positive inoculum effect and penetrates poorly into the core of multicellular tumour spheroids (MTS). Cis-platin (DDP) displays neither of these characteristics. We evaluated whether combining these 2 agents would influence the cell kill effect at a tumour mass level. MTS wer...

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Detalles Bibliográficos
Autores principales: Kohno, N., Ohnuma, T., Kaneko, M., Holland, J. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246593/
https://www.ncbi.nlm.nih.gov/pubmed/3179185