Cytotoxicity of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MTIC) on Mer+, Mer+Rem- and Mer- cell lines: differential potentiation by 3-acetamidobenzamide.

Mechanisms of resistance to the active metabolite 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MTIC) of the drug 5-(3,3-dimethyl-1-triázeno)imidazole-4-carboxamide (DTIC) were studied in three human cell lines with differing amounts of the repair enzyme O6-alkylguanine-DNA alkyltransferase (O6AT)...

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Detalles Bibliográficos
Autores principales: Lunn, J. M., Harris, A. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246699/
https://www.ncbi.nlm.nih.gov/pubmed/2831926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246699/
https://www.ncbi.nlm.nih.gov/pubmed/2831926

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