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Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine.

The vaso-active drug hydralazine causes a considerable increase in the cytotoxic effect of melphalan towards the KHT tumour in mice. The enhancement in response, measured as the concentration of melphalan required to achieve a given tumour response, is 3.0 and 2.35 when determined using the regrowth...

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Detalles Bibliográficos
Autores principales: Stratford, I. J., Adams, G. E., Godden, J., Nolan, J., Howells, N., Timpson, N.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246762/
https://www.ncbi.nlm.nih.gov/pubmed/3166900