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Partial deletion of chromosome 11p in breast cancer correlates with size of primary tumour and oestrogen receptor level.

In a study of DNAs from 100 breast cancer patients and 100 controls, there were no differences in the frequencies of common or rare alleles at the Harvey ras (c-Ha-ras) locus on chromosome 11. However, one Ha-ras allele was deleted from the tumour DNA in 14 of 65 informative patients. Loss of a Ha-r...

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Detalles Bibliográficos
Autores principales: Mackay, J., Elder, P. A., Porteous, D. J., Steel, C. M., Hawkins, R. A., Going, J. J., Chetty, U.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246883/
https://www.ncbi.nlm.nih.gov/pubmed/3066395