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Warfarin inhibits metastasis of Mtln3 rat mammary carcinoma without affecting primary tumour growth.

Coumarin anticoagulants inhibit metastasis in several animal models, but the mechanism of this effect is uncertain. In order to determine the role of cytotoxic and/or cytostatic actions of coumarins on the tumour cells, we have studied the effects of warfarin on tumour cell growth in a model in whic...

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Detalles Bibliográficos
Autores principales: McCulloch, P., George, W. D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247008/
https://www.ncbi.nlm.nih.gov/pubmed/2930682