Chlorpromazine reduces UV-induced squamous cell carcinogenesis in hairless mice and enhances UV-induced DNA damage in cultured cells.

Administration of the photoactivable compound chlorpromazine (CPZ) to SKH-1 hairless mice via their drinking water (CPZ, 0.01%) significantly reduced the rates of accumulation and yields of squamous cell carcinomas induced by long-term repeated exposures of these animals to solar UV radiation. This...

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Detalles Bibliográficos
Autores principales: Peak, M. J., Pfaff, M., Peraino, C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247052/
https://www.ncbi.nlm.nih.gov/pubmed/2765369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247052/
https://www.ncbi.nlm.nih.gov/pubmed/2765369

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