Cargando…

Potentiation of methotrexate lymphocytotoxicity in vitro by inhibitors of nucleoside transport.

Modulation of nucleic acid antimetabolite cytotoxicity by preformed purines and pyrimidines may not only complicate the interpretation of drug sensitivity tests and other in vitro studies but also adversely affect treatment in vivo. Previously we reported that in a lymphocyte clonal assay, thymidine...

Descripción completa

Detalles Bibliográficos
Autores principales: Hughes, J. M., Tattersall, M. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247054/
https://www.ncbi.nlm.nih.gov/pubmed/2930702