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Clonal allele loss in gastrointestinal cancers.

Using a panel of DNA probes for hypervariable DNA regions we screened 52 gastrointestinal carcinomas for clonal allele losses on chromosomes 1, 5, 7, 12, 16 and 17. A total of 24/35 informative cases of colorectal cancers showed loss of constitutional heterozygosity at a locus on chromosome 17p, whi...

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Detalles Bibliográficos
Autores principales: Fey, M. F., Hesketh, C., Wainscoat, J. S., Gendler, S., Thein, S. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247214/
https://www.ncbi.nlm.nih.gov/pubmed/2736209