Inhibition of vincristine binding to plasma membrane vesicles from daunorubicin-resistant Ehrlich ascites cells by multidrug resistance modulators.

The multidrug resistance (MDR) phenotype is presumed to be mostly dependent on changes in the resistant cell plasma membrane, notably the emergence of a 170 kDa glycoprotein called P-glycoprotein, which facilitate increased drug efflux. We have previously demonstrated that ATP-enhanced binding of vi...

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Detalles Bibliográficos
Autores principales: Sehested, M., Jensen, P. B., Skovsgaard, T., Bindslev, N., Demant, E. J., Friche, E., Vindeløv, L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247270/
https://www.ncbi.nlm.nih.gov/pubmed/2605092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247270/
https://www.ncbi.nlm.nih.gov/pubmed/2605092

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