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Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer

BACKGROUND: Cervical carcinogenesis is a multistep process initiated by "high risk" human papillomaviruses (HR-HPV), most commonly HPV16. The infection per se is, however, not sufficient to induce malignant conversion. Transforming Growth Factor β (TGF-β) inhibits epithelial proliferation...

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Detalles Bibliográficos
Autores principales: Diaz-Chavez, Jose, Hernandez-Pando, Rogelio, Lambert, Paul F, Gariglio, Patricio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248208/
https://www.ncbi.nlm.nih.gov/pubmed/18184435
http://dx.doi.org/10.1186/1476-4598-7-3