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On the role of transforming growth factor-β in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells

BACKGROUND: Retinoids are potent growth inhibitory and differentiating agents in a variety of cancer cell types. We have shown that retinoids induce growth arrest in all pancreatic cancer cell lines studied, regardless of their p53 and differentiation status. However, the mechanism of growth inhibit...

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Detalles Bibliográficos
Autores principales: Singh, Brahmchetna, Murphy, Richard F, Ding, Xian-Zhong, Roginsky, Alexandra B, Bell, Richard H, Adrian, Thomas E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248210/
https://www.ncbi.nlm.nih.gov/pubmed/18157915
http://dx.doi.org/10.1186/1476-4598-6-82