Cargando…

On the role of transforming growth factor-β in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells

BACKGROUND: Retinoids are potent growth inhibitory and differentiating agents in a variety of cancer cell types. We have shown that retinoids induce growth arrest in all pancreatic cancer cell lines studied, regardless of their p53 and differentiation status. However, the mechanism of growth inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Brahmchetna, Murphy, Richard F, Ding, Xian-Zhong, Roginsky, Alexandra B, Bell, Richard H, Adrian, Thomas E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248210/ https://www.ncbi.nlm.nih.gov/pubmed/18157915 http://dx.doi.org/10.1186/1476-4598-6-82

Ejemplares similares

Loss of growth inhibitory effects of retinoic acid in human breast cancer cells following long-term exposure to retinoic acid
por: Stephen, R, et al.
Publicado: (2000)

Retinoic acid promotes myogenesis in myoblasts by antagonizing transforming growth factor-beta signaling via C/EBPβ
por: Lamarche, Émilie, et al.
Publicado: (2015)

The Effects of Retinoic Acid and MAPK Inhibitors on Phosphorylation of Smad2/3 Induced by Transforming Growth Factor β1
por: Lee, Sang Hoon, et al.
Publicado: (2019)

Disruption of Retinoic Acid Receptor Alpha Reveals the Growth Promoter Face of Retinoic Acid
por: Somenzi, Giulia, et al.
Publicado: (2007)

Effects of retinoic acid on compensatory lung growth
por: Karapolat, Sami, et al.
Publicado: (2008)

Cyp26b1 Regulates Retinoic Acid-Dependent Signals in T Cells and Its Expression Is Inhibited by Transforming Growth Factor-β
por: Takeuchi, Hajime, et al.
Publicado: (2011)

Inhibitory Action of Transforming Growth Factor‐β on Induction of Differentiation of Myeloid Leukemia Cells
por: Okabe‐Kado, Junko, et al.
Publicado: (1989)

Suppression of Latent Transforming Growth Factor (TGF)-β1 Restores Growth Inhibitory TGF-β Signaling through microRNAs
por: Dogar, Afzal M., et al.
Publicado: (2011)

Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth
por: Patel, J B, et al.
Publicado: (2007)

Reduced Retinoic Acid Receptor Beta (Rarβ) Affects Pancreatic β-Cell Physiology
por: Khalique, Anila, et al.
Publicado: (2022)

Overexpression of Retinoic Acid Receptor β Induces Growth Arrest and Apoptosis in Oral Cancer Cell Lines
por: Hayashi, Ken, et al.
Publicado: (2001)

Transforming growth factor-β and breast cancer: Tumor promoting effects of transforming growth factor-β
por: Dumont, Nancy, et al.
Publicado: (2000)

Retinoic acid decreases ATF-2 phosphorylation and sensitizes melanoma cells to taxol-mediated growth inhibition
por: Huang, Ying, et al.
Publicado: (2008)

Transforming growth factor-β and breast cancer: Transforming growth factor-β/SMAD signaling defects and cancer
por: Kretzschmar, Marcus
Publicado: (2000)

Retinoic acid stimulates annexin-mediated growth plate chondrocyte mineralization
por: Wang, Wei, et al.
Publicado: (2002)

Growth‐promoting Effect of Retinoic Acid in Transplantable Pituitary Tumor of Rat
por: Roy, Bidyut, et al.
Publicado: (1990)

Transforming growth factor-β1 impairs neuropathic pain through pleiotropic effects
por: Echeverry, Stefania, et al.
Publicado: (2009)

Role of transforming growth factor-β in peripheral nerve regeneration
por: Ding, Zihan, et al.
Publicado: (2023)

Retinoic Acid Promotes the Generation of Pancreatic Endocrine Progenitor Cells and Their Further Differentiation into β-Cells
por: Öström, Maria, et al.
Publicado: (2008)

Estrogen Protects Lenses against Cataract Induced by Transforming Growth Factor-β (TGFβ)
por: Hales, Angela M., et al.
Publicado: (1997)

Inhibitory Effects of Resveratrol on Airway Remodeling by Transforming Growth Factor-β/Smad Signaling Pathway in Chronic Asthma Model
por: Lee, Hwa Young, et al.
Publicado: (2017)

Transforming growth factor–β in tissue fibrosis
por: Frangogiannis, Nikolaos G.
Publicado: (2020)

Transforming growth factor-β in tumour development
por: Trelford, Charles B., et al.
Publicado: (2022)

Transforming growth factor-β and breast cancer: Cell cycle arrest by transforming growth factor-β and its disruption in cancer
por: Donovan, Jeffrey, et al.
Publicado: (2000)

Modulation of Growth Factor Receptors on Acute Myeloblastic Leukemia Cells by Retinoic Acid
por: Tohda, Shuji, et al.
Publicado: (1994)

Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid
por: Terao, Mineko, et al.
Publicado: (2019)

All-Trans Retinoic Acid Effect on Candida albicans Growth and Biofilm Formation
por: Pistoia, Enrico Salvatore, et al.
Publicado: (2022)

All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E(2) in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages
por: Ho, Victor W., et al.
Publicado: (2016)

Androgen and retinoic acid interaction in LNCaP cells, effects on cell proliferation and expression of retinoic acid receptors and epidermal growth factor receptor
por: Li, Ming-tang, et al.
Publicado: (2002)

Mechanism of Transforming Growth Factor β–induced Inhibition of T Helper Type 1 Differentiation
por: Gorelik, Leonid, et al.
Publicado: (2002)

Transforming growth factor‐β in liver cancer stem cells and regeneration
por: Rao, Shuyun, et al.
Publicado: (2017)

Retinoic acid receptor alpha mediates growth inhibition by retinoids in rat pancreatic carcinoma DSL-6A/C1 cells.
por: Brembeck, F. H., et al.
Publicado: (1998)

Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice
por: Huynh, C K, et al.
Publicado: (2006)

Targeting transforming growth factor-β signaling for enhanced cancer chemotherapy
por: Chen, Jitang, et al.
Publicado: (2021)

Antagonists of retinoic acid receptors (RARs) are potent growth inhibitors of prostate carcinoma cells
por: Hammond, L A, et al.
Publicado: (2001)

Resveratrol Suppresses the Growth and Enhances Retinoic Acid Sensitivity of Anaplastic Thyroid Cancer Cells
por: Li, Yi-Tian, et al.
Publicado: (2018)

Correction to: Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid
por: Terao, Mineko, et al.
Publicado: (2019)

T Cell Death and Transforming Growth Factor β1
por: Golstein, Pierre, et al.
Publicado: (2001)

Transforming growth factor-β and breast cancer: Introduction
por: Slingerland, Joyce
Publicado: (2000)

Transforming growth factor-β1 in plaque morphea
por: Dańczak-Pazdrowska, Aleksandra, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vspnvk3p34td38u2onkvj7dcns